| [1] |
Rawla P, Sunkara T, Barsouk A. Epidemiology of colorectal cancer: incidence, mortality, survival, and risk factors. Prz Gastroenterol. 2019;14(2):89–103. https://doi.org/10.5114/pg.2018.81072. doi: 10.5114/pg.2018.81072 |
| [2] |
Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015;136(5):E359–86. https://doi.org/10.1002/ijc.29210. doi: 10.1002/ijc.29210 |
| [3] |
Kazemi E, Zayeri F, Baghestani A, Bakhshandeh M, Hafizi M. Trends of colorectal cancer incidence, prevalence and mortality in worldwide from 1990 to 2017. Iran J Public Health. 2023;52(2):436–45. https://doi.org/10.18502/ijph.v52i2.11897. doi: 10.18502/ijph.v52i2.11897 |
| [4] |
Cardoso R, Guo F, Heisser T, Hackl M, Ihle P, De Schutter H, et al. Colorectal cancer incidence, mortality, and stage distribution in European countries in the colorectal cancer screening era: an international population-based study. Lancet Oncol. 2021;22(7):1002–13. https://doi.org/10.1016/S1470-2045(21)00199-6. doi: 10.1016/S1470-2045(21)00199-6 |
| [5] |
Ernest Miles W. A method of performing abdomino-perineal excision for carcinoma of the rectum and of the terminal portion of the pelvic colon. Lancet. 1908;172(4451):1812–3. https://doi.org/10.1016/s0140-6736(00)99076-7. doi: 10.1016/s0140-6736(00)99076-7 |
| [6] |
Kajmolli A, McGuirk M, Gachabayov M, Bergamaschi R, Latifi R. Evolution of the circular stapler in rectal cancer surgery. Surg Technol Int. 2020;37:99–101. |
| [7] |
Heald RJ, Ryall RDH. Recurrence and survival after total mesorectal excision for rectal cancer. Lancet. 1986;327(8496):1479–82. https://doi.org/10.1016/s0140-6736(86)91510-2. doi: 10.1016/s0140-6736(86)91510-2 |
| [8] |
Nastro P, Beral D, Hartley J, Monson JRT. Local excision of rectal cancer: review of literature. Dig Surg. 2005;22(1–2):6–15. https://doi.org/10.1159/000084345. doi: 10.1159/000084345 |
| [9] |
Knol J, Keller DS. Total mesorectal excision technique- past, present, and future. Clin Colon Rectal Surg. 2020;33(3):134–43. https://doi.org/10.1055/s-0039-3402776. doi: 10.1055/s-0039-3402776 |
| [10] |
Hu XY, Jiang Z, Zhang MG, Wang XS. Current research status on pelvic autonomic nerve monitoring in rectal cancer surgery. Chin J Gastrointest Surg. 2022;25(1):82–8. https://doi.org/10.3760/cma.j.cn441530-20210324-00130. doi: 10.3760/cma.j.cn441530-20210324-00130 |
| [11] |
Kosinski L, Habr-Gama A, Ludwig K, Perez R. Shifting concepts in rectal cancer management: a review of contemporary primary rectal cancer treatment strategies. CA Cancer J Clin. 2012;62(3):173–202. https://doi.org/10.3322/caac.21138. doi: 10.3322/caac.21138 |
| [12] |
Buess G, Theiss R, Hutterer F, Pichlmaier H, Pelz C, Holfeld T, et al. Die transanale endoskopische Rektumoperation – Erprobung einer neuen Methode im Tierversuch. Leber Magen Darm. 1983;13(2):73–7. |
| [13] |
Atallah S, Albert M, Larach S. Transanal minimally invasive surgery: a giant leap forward. Surg Endosc. 2010;24(9):2200–5. https://doi.org/10.1007/s00464-010-0927-z. doi: 10.1007/s00464-010-0927-z |
| [14] |
Maggiori L, Panis Y. Transanal endoscopic microsurgery (TEM) for T1 rectal cancer. Acta Chir Iugosl. 2012;59(2):87–90. https://doi.org/10.2298/aci1202087m. doi: 10.2298/aci1202087m |
| [15] |
Bai J, Gao J, Mao Z, Wang J, Li J, Li W, et al. Genetic mutations in human rectal cancers detected by targeted sequencing. J Hum Genet. 2015;60(10):589–96. https://doi.org/10.1038/jhg.2015.71. doi: 10.1038/jhg.2015.71 |
| [16] |
Rouleau-Fournier F, Brown CJ. Can less be more? Organ preservation strategies in the management of rectal cancer. Curr Oncol. 2019;26(Suppl 1):S16–23. https://doi.org/10.3747/co.26.5841. doi: 10.3747/co.26.5841 |
| [17] |
Martens MH, Maas M, Heijnen LA, Lambregts DMJ, Leijtens JWA, Stassen LPS, et al. Long-term outcome of an organ preservation program after neoadjuvant treatment for rectal cancer. J Natl Cancer Inst. 2016;108(12):djw171. https://doi.org/10.1093/jnci/djw171. doi: 10.1093/jnci/djw171 |
| [18] |
Wlodarczyk JR, Lee SW. New frontiers in management of early and advanced rectal cancer. Cancers. 2022;14(4):938. https://doi.org/10.3390/cancers14040938. doi: 10.3390/cancers14040938 |
| [19] |
Neilson LJ, Rutter MD, Saunders BP, Plumb A, Rees CJ. Assessment and management of the malignant colorectal polyp. Frontline Gastroenterol. 2015;6(2):117–26. https://doi.org/10.1136/flgastro-2015-100565. doi: 10.1136/flgastro-2015-100565 |
| [20] |
Haggitt RC, Glotzbach RE, Soffer EE, Wruble LD. Prognostic factors in colorectal carcinomas arising in adenomas: implications for lesions removed by endoscopic polypectomy. Gastroenterology. 1985;89(2):328–36. https://doi.org/10.1016/0016-5085(85)90333-6. doi: 10.1016/0016-5085(85)90333-6 |
| [21] |
Kikuchi R, Takano M, Takagi K, Fujimoto N, Nozaki R, Fujiyoshi T, et al. Management of early invasive colorectal cancer - risk of recurrence and clinical guidelines. Dis Colon Rectum. 1995;38(12):1286–95. https://doi.org/10.1007/BF02049154. doi: 10.1007/BF02049154 |
| [22] |
Barel F, Cariou M, Saliou P, Kermarrec T, Auffret A, Samaison L, et al. Histopathological factors help to predict lymph node metastases more efficiently than extranodal recurrences in submucosa invading pT1 colorectal cancer. Sci Rep. 2019;9(1):8342. https://doi.org/10.1038/s41598-019-44894-w. doi: 10.1038/s41598-019-44894-w |
| [23] |
Kim MJ, Lee TG. Transanal minimally invasive surgery using laparoscopic instruments of the rectum: a review. World J Gastrointest Surg. 2021;13(10):1149–65. https://doi.org/10.4240/wjgs.v13.i10.1149. doi: 10.4240/wjgs.v13.i10.1149 |
| [24] |
Read M, Felder S. Transanal approaches to rectal neoplasia. Semin Colon Rectal Surg. 2022;33(3):100899. https://doi.org/10.1016/j.scrs.2022.100899. doi: 10.1016/j.scrs.2022.100899 |
| [25] |
Beets-Tan RGH, Lambregts DMJ, Maas M, Bipat S, Barbaro B, Curvo-Semedo L, et al. Magnetic resonance imaging for clinical management of rectal cancer: updated recommendations from the 2016 European Society of Gastrointestinal and Abdominal Radiology (ESGAR) consensus meeting. Eur Radiol. 2018;28(4):1465–75. https://doi.org/10.1007/s00330-017-5026-2. doi: 10.1007/s00330-017-5026-2 |
| [26] |
Tarantino I, Warschkow R, Worni M, Merati-Kashani K, Köberle D, Schmied BM, et al. Elevated preoperative CEA is associated with worse survival in stage Ⅰ-Ⅲ rectal cancer patients. Br J Cancer. 2012;107(2):266–74. https://doi.org/10.1038/bjc.2012.267. doi: 10.1038/bjc.2012.267 |
| [27] |
Keller DS, Berho M, Perez RO, Wexner SD, Chand M. The multidisciplinary management of rectal cancer. Nat Rev Gastroenterol Hepatol. 2020;17(7):414–29. https://doi.org/10.1038/s41575-020-0275-y. doi: 10.1038/s41575-020-0275-y |
| [28] |
Glynne-Jones R, Wyrwicz L, Tiret E, Brown G, Rödel C, Cervantes A, et al. Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2017;28(Suppl l_4):iv22–40. https://doi.org/10.1093/annonc/mdx224. doi: 10.1093/annonc/mdx224 |
| [29] |
You YN, Hardiman KM, Bafford A, Poylin V, Francone TD, Davis K, et al. The American society of colon and rectal surgeons clinical Practice guidelines for the management of rectal cancer. Dis Colon Rectum. 2020;63(9):1191–222. https://doi.org/10.1097/DCR.0000000000001762. doi: 10.1097/DCR.0000000000001762 |
| [30] |
Liebig-Hörl G, Puchner C, Gerken M, Klinkhammer-Schalke M, Fürst A. Treatment strategy for early stage rectal cancer (T1 carcinoma). Chirurg. 2018;89(5):358–64. https://doi.org/10.1007/s00104-018-0603-8. doi: 10.1007/s00104-018-0603-8 |
| [31] |
Murray JJ, Stahl TJ. Sphincter-saving alternatives for treatment of adenocarcinoma involving distal rectum. Surg Clin North Am. 1993;73(1):131–44. https://doi.org/10.1016/s0039-6109(16)45933-5. doi: 10.1016/s0039-6109(16)45933-5 |
| [32] |
Sharma A, Hartley J, Monson JRT. Local excision of rectal tumors. Surg Oncol. 2003;12(1):51–61. https://doi.org/10.1016/s0960-7404(03)00007-0. doi: 10.1016/s0960-7404(03)00007-0 |
| [33] |
Tytherleigh MG, Warren BF, Mortensen NJMC. Management of early rectal cancer. Br J Surg. 2008;95(4):409–23. https://doi.org/10.1002/bjs.6127. doi: 10.1002/bjs.6127 |
| [34] |
Allaix ME, Arezzo A, Morino M. Transanal treatment of rectal cancer by rigid platform. Ann Laparosc Endosc Surg. 2018;3:45. https://doi.org/10.21037/ales.2018.05.03. doi: 10.21037/ales.2018.05.03 |
| [35] |
Xue X, Lin G. Transanal endoscopic microsurgery: exploring its indications and novel applications. A narrative review. Wideochir Inne Tech Maloinwazyjne. 2022;17(1):95–103. https://doi.org/10.5114/wiitm.2021.108811. doi: 10.5114/wiitm.2021.108811 |
| [36] |
Leong KJ, Evans J, Davies MM, Scott A, Lidder P. Transanal endoscopic surgery: past, present and future. Br J Hosp Med. 2016;77(7):394–402. https://doi.org/10.12968/hmed.2016.77.7.394. doi: 10.12968/hmed.2016.77.7.394 |
| [37] |
Allaix ME, Arezzo A, Nestorović M, Galosi B, Morino M. Local excision for rectal cancer: a minimally invasive option. Minerva Chir. 2018;73(6):548–57. https://doi.org/10.23736/S0026-4733.18.07702-7. doi: 10.23736/S0026-4733.18.07702-7 |
| [38] |
Saclarides T. Transanal endoscopic microsurgery. Clin Colon Rectal Surg. 2015;28(3):165–75. https://doi.org/10.1055/s-0035-1562889. doi: 10.1055/s-0035-1562889 |
| [39] |
Allaix ME, Arezzo A, Festa F, Morino M. Teo (transanal endoscopic operation) for rectal lesions using two-dimensional screen visualization and standard laparoscopic instruments. Eur Surg Res. 2010;45(3–4). |
| [40] |
Serra-Aracil X, Campos-Serra A, MoraLópez L, Serra-Pla S, Pallisera-Lloveras A, Flores-Clotet R, et al. Is local resection of anal canal tumors feasible with transanal endoscopic surgery? World J Surg. 2020;44(3):939–46. https://doi.org/10.1007/s00268-019-05262-x. doi: 10.1007/s00268-019-05262-x |
| [41] |
Maya A, Vorenberg A, Oviedo M, Da Silva G, Wexner SD, Sands D. Learning curve for transanal endoscopic microsurgery: a single-center experience. Surg Endosc. 2014;28(5):1407–12. https://doi.org/10.1007/s00464-013-3341-5. doi: 10.1007/s00464-013-3341-5 |
| [42] |
Talbott VA, Whiteford MH. Complications of transanal endoscopic surgery. Semin Colon Rectal Surg. 2015;26(1):32–5. https://doi.org/10.1053/j.scrs.2014.10.008. doi: 10.1053/j.scrs.2014.10.008 |
| [43] |
Marques CFS, Nahas CSR, Ribeiro U, Bustamante LA, Pinto RA, Mory EK, et al. Postoperative complications in the treatment of rectal neoplasia by transanal endoscopic microsurgery: a prospective study of risk factors and time course. Int J Colorectal Dis. 2016;31(4):833–41. https://doi.org/10.1007/s00384-016-2527-4. doi: 10.1007/s00384-016-2527-4 |
| [44] |
Serra-Aracil X, Mora-Lopez L, Alcantara-Moral M, Caro-Tarrago A, Navarro-Soto S. Transanal endoscopic microsurgery with 3-D (TEM) or high-definition 2-D transanal endoscopic operation (TEO) for rectal tumors. A prospective, randomized clinical trial. Int J Colorectal Dis. 2014;29(5):605–10. https://doi.org/10.1007/s00384-014-1849-3. doi: 10.1007/s00384-014-1849-3 |
| [45] |
Rimonda R, Arezzo A, Arolfo S, Salvai A, Morino M. TransAnal minimally invasive surgery (TAMIS) with SILSTM port versus transanal endoscopic microsurgery (TEM): a comparative experimental study. Surg Endosc. 2013;27(10):3762–8. https://doi.org/10.1007/s00464-013-2962-z. doi: 10.1007/s00464-013-2962-z |
| [46] |
Mehraj A, Saqib N, Wani R, Chowdri N, Parray F, Khan M. Transanal minimal invasive surgery (TAMIS): safety and feasibility for the resection of benign and malignant lesions of the rectum. Turk J Surg. 2021;37(1):6–12. https://doi.org/10.47717/turkjsurg.2021.5057. doi: 10.47717/turkjsurg.2021.5057 |
| [47] |
McLemore EC, Weston LA, Coker AM, Jacobsen GR, Talamini MA, Horgan S, et al. Transanal minimally invasive surgery for benign and malignant rectal neoplasia. Am J Surg. 2014;208(3):372–81. https://doi.org/10.1016/j.amjsurg.2014.01.006. doi: 10.1016/j.amjsurg.2014.01.006 |
| [48] |
Lee L, Burke JP, Debeche-Adams T, Nassif G, Martin-Perez B, Monson JRT, et al. Transanal minimally invasive surgery for local excision of benign and malignant rectal neoplasia: outcomes from 200 consecutive cases with midterm follow up. Ann Surg. 2018;267(5):910–6. https://doi.org/10.1097/SLA.0000000000002190. doi: 10.1097/SLA.0000000000002190 |
| [49] |
Lim SB, Seo SI, Lee JL, Kwak JY, Jang TY, Kim CW, et al. Feasibility of transanal minimally invasive surgery for mid-rectal lesions. Surg Endosc. 2012;26(11):3127–32. https://doi.org/10.1007/s00464-012-2303-7. doi: 10.1007/s00464-012-2303-7 |
| [50] |
Lee TG, Lee SJ. Transanal single-port microsurgery for rectal tumors: minimal invasive surgery under spinal anesthesia. Surg Endosc. 2014;28(1):271–80. https://doi.org/10.1007/s00464-013-3184-0. doi: 10.1007/s00464-013-3184-0 |
| [51] |
Christoforidis D, Cho HM, Dixon MR, Mellgren AF, Madoff RD, Finne CO. Transanal endoscopic microsurgery versus conventional transanal excision for patients with early rectal cancer. Ann Surg. 2009;249(5):776–82. https://doi.org/10.1097/SLA.0b013e3181a3e54b. doi: 10.1097/SLA.0b013e3181a3e54b |
| [52] |
Warren E, Gamboa AC, Medin C, Hendren S, Regenbogen SE, Holder-Murray J, et al. Association of transanal minimally invasive surgical approach with oncologic outcomes over conventional transanal excision for early-stage rectal cancer: an analysis of the US Rectal Cancer Consortium. J Clin Oncol. 2023;41(4_Suppl l):145. https://doi.org/10.1200/jco.2023.41.4_suppl.145. doi: 10.1200/jco.2023.41.4_suppl.145 |
| [53] |
Clancy C, Burke JP, Albert MR, O’Connell PR, Winter DC. Transanal endoscopic microsurgery versus standard transanal excision for the removal of rectal neoplasms: a systematic review and meta-analysis. Dis Colon Rectum. 2015;58(2):254–61. https://doi.org/10.1097/DCR.0000000000000309. doi: 10.1097/DCR.0000000000000309 |
| [54] |
Melin AA, Kalaskar S, Taylor L, Thompson JS, Ternent C, Langenfeld SJ. Transanal endoscopic microsurgery and transanal minimally invasive surgery: is one technique superior? Am J Surg. 2016;212(6):1063–7. https://doi.org/10.1016/j.amjsurg.2016.08.017. doi: 10.1016/j.amjsurg.2016.08.017 |
| [55] |
Kaymak Ş, Sinan H, Saydam M, Aktaş HH, Gecim E, Demirbas S. Comparison of transanal minimally invasive surgery (TAMIS) and transanal endoscopic operations (TEO). Indian J Surg. 2020;82(3):319–24. https://doi.org/10.1007/s12262-019-01943-y. doi: 10.1007/s12262-019-01943-y |
| [56] |
Mege D, Bridoux V, Maggiori L, Tuech JJ, Panis Y. What is the best tool for transanal endoscopic microsurgery (TEM)? A casematched study in 74 patients comparing a standard platform and a disposable material. Int J Colorectal Dis. 2017;32(7):1041–5. https://doi.org/10.1007/s00384-016-2733-0. doi: 10.1007/s00384-016-2733-0 |
| [57] |
Stipa F, Tierno SM, Russo G, Burza A. Transanal minimally invasive surgery (TAMIS) versus trans-anal endoscopic microsurgery (TEM): a comparative case–control matchedpairs analysis. Surg Endosc. 2022;36(3):2081–6. https://doi.org/10.1007/s00464-021-08494-y. doi: 10.1007/s00464-021-08494-y |
| [58] |
Lee L, Edwards K, Hunter IA, Hartley JE, Atallah SB, Albert MR, et al. Quality of local excision for rectal neoplasms using transanal endoscopic microsurgery versus transanal minimally invasive surgery: a multi-institutional matched analysis. Dis Colon Rectum. 2017;60(9):928–35. https://doi.org/10.1097/DCR.0000000000000884. doi: 10.1097/DCR.0000000000000884 |
| [59] |
Sylla P, Rattner DW, Delgado S, Lacy AM. NOTES transanal rectal cancer resection using transanal endoscopic microsurgery and laparoscopic assistance. Surg Endosc. 2010;24(5):1205–10. https://doi.org/10.1007/s00464-010-0965-6. doi: 10.1007/s00464-010-0965-6 |
| [60] |
Ma B, Gao P, Song Y, Zhang C, Zhang C, Wang L, et al. Transanal total mesorectal excision (taTME) for rectal cancer: a systematic review and meta-analysis of oncological and perioperative outcomes compared with laparoscopic total mesorectal excision. BMC Cancer. 2016;16(1):380. https://doi.org/10.1186/s12885-016-2428-5. doi: 10.1186/s12885-016-2428-5 |
| [61] |
Franke AJ, Skelton WP, George TJ, Iqbal A. A comprehensive review of randomized clinical trials shaping the landscape of rectal cancer therapy. Colorectal Cancer. 2021;20(1):1–19. https://doi.org/10.1016/j.clcc.2020.07.009.Clin. doi: 10.1016/j.clcc.2020.07.009 |
| [62] |
Winde G, Nottberg H, Keller R, Schmid KW, Bünte H. Surgical cure for early rectal carcinomas (T1): transanal endoscopic microsurgery vs. anterior resection. Dis Colon Rectum. 1996;39(9):969–76. https://doi.org/10.1007/BF02054683. doi: 10.1007/BF02054683 |
| [63] |
Kidane B, Chadi SA, Kanters S, Colquhoun PH, Ott MC. Local resection compared with radical resection in the treatment of T1N0M0 rectal adenocarcinoma: a systematic review and meta-analysis. Dis Colon Rectum. 2015;58(1):122–40. https://doi.org/10.1097/DCR.0000000000000293. doi: 10.1097/DCR.0000000000000293 |
| [64] |
Lu JY, Lin GL, Qiu HZ, Xiao Y, Wu B, Zhou JL. Comparison of transanal endoscopic microsurgery and total mesorectal excision in the treatment of T1 rectal cancer: a meta-analysis. PLoS One. 2015;10(10):e0141427. https://doi.org/10.1371/journal.pone.0141427. doi: 10.1371/journal.pone.0141427 |
| [65] |
Elhaj A, O’Reilly M, Mulligan E. Transanal endoscopic microsurgery (TEM) for early rectal cancer. Ir Med J. 2021;114(9). |
| [66] |
Türler A, Schäfer H, Pichlmaier H. Role of transanal endoscopic microsurgery in the palliative treatment of rectal cancer. Scand J Gastroenterol. 1997;32(1):58–61. https://doi.org/10.3109/00365529709025064. doi: 10.3109/00365529709025064 |
| [67] |
Tsai BM, Finne CO, Nordenstam JF, Christoforidis D, Madoff RD, Mellgren A. Transanal endoscopic microsurgery resection of rectal tumors: outcomes and recommendations. Dis Colon Rectum. 2010;53(1):16–23. https://doi.org/10.1007/DCR.0b013e3181bbd6ee. doi: 10.1007/DCR.0b013e3181bbd6ee |
| [68] |
Benoist S. Transanal excision of rectal tumours: indications, techniques, results and complications. Hépato-Gastro. 2016;23(2). |
| [69] |
Serra-Aracil X, Serra-Pla S, Mora-Lopez L, Pallisera-Lloveras A, Labro-Ciurans M, Navarro-Soto S. Transanal endoscopic micro-surgery in elderly and very elderly patients: a safe option? Observational study with prospective data collection. Surg Endosc. 2019;33(1):184–91. https://doi.org/10.1007/s00464-018-6292-z. doi: 10.1007/s00464-018-6292-z |
| [70] |
Arezzo A, Cortese G, Arolfo S, Bullano A, Passera R, Galietti E, et al. Transanal endoscopic operation under spinal anaesthesia. Br J Surg. 2016;103(7):916–20. https://doi.org/10.1002/bjs.10082. doi: 10.1002/bjs.10082 |
| [71] |
Berger Y, Gingold-Belfer R, Khatib M, Yassin M, Khoury W, Schmilovitz-Weiss H, et al. Transanal endoscopic microsurgery under spinal anaesthesia. J Minim Access Surg. 2021;17(4):490–4. https://doi.org/10.4103/jmas.JMAS_144_20. doi: 10.4103/jmas.JMAS_144_20 |
| [72] |
Elmessiry MM, Van Koughnett JAM, Maya A, Dasilva G, Wexner SD, Bejarano P, et al. Local excision of T1 and T2 rectal cancer: proceed with caution. Colorectal Dis. 2014;16(9):703–9. https://doi.org/10.1111/codi.12657. doi: 10.1111/codi.12657 |
| [73] |
Lezoche E, Baldarelli M, Lezoche G, Paganini AM, Gesuita R, Guerrieri M. Randomized clinical trial of endoluminal locoregional resection versus laparoscopic total mesorectal excision for T2 rectal cancer after neoadjuvant therapy. Br J Surg. 2012;99(9):1211–8. https://doi.org/10.1002/bjs.8821. doi: 10.1002/bjs.8821 |
| [74] |
Rullier E, Rouanet P, Tuech JJ, Valverde A, Lelong B, Rivoire M, et al. Organ preservation for rectal cancer (GRECCAR 2): a prospective, randomised, open-label, multicentre, phase 3 trial. Lancet. 2017;390(10093):469–79. https://doi.org/10.1016/S0140-6736(17)31056-5. doi: 10.1016/S0140-6736(17)31056-5 |
| [75] |
Rullier E, Vendrely V, Asselineau J, Rouanet P, Tuech JJ, Valverde A, et al. Organ preservation with chemoradiotherapy plus local excision for rectal cancer: 5-year results of the GRECCAR 2 randomised trial. Lancet Gastroenterol Hepatol. 2020;5(5):465–74. https://doi.org/10.1016/S2468-1253(19)30410-8. doi: 10.1016/S2468-1253(19)30410-8 |
| [76] |
Stijns RCH, De Graaf EJR, Punt CJA, Nagtegaal ID, Nuyttens JJME, Van Meerten E, et al. Long-term oncological and functional outcomes of chemoradiotherapy followed by organ-sparing transanal endoscopic microsurgery for distal rectal cancer: the CARTS study. JAMA Surg. 2019;154(1):47–54. https://doi.org/10.1001/jamasurg.2018.3752. doi: 10.1001/jamasurg.2018.3752 |
| [77] |
Bach SP, Gilbert A, Brock K, Korsgen S, Geh I, Hill J, et al. Radical surgery versus organ preservation via short-course radiotherapy followed by transanal endoscopic microsurgery for early-stage rectal cancer (TREC): a randomised, open-label feasibility study. Lancet Gastroenterol Hepatol. 2021;6(2):92–105. https://doi.org/10.1016/S2468-1253(20)30333-2. doi: 10.1016/S2468-1253(20)30333-2 |
| [78] |
Kennecke HF, O’Callaghan CJ, Loree JM, Moloo H, Auer R, Jonker DJ, et al. Neoadjuvant chemotherapy, excision, and observation for early rectal cancer: the phase Ⅱ NEO trial (CCTG CO.28) primary end point results. J Clin Oncol. 2023;41(2):233–42. https://doi.org/10.1200/JCO.22.00184. doi: 10.1200/JCO.22.00184 |
| [79] |
Xiong X, Wang C, Wang B, Shen Z, Jiang K, Gao Z, et al. Can transanal endoscopic microsurgery effectively treat T1 or T2 rectal cancer? A systematic review and meta-analysis. Surg Oncol. 2021;37:101561. https://doi.org/10.1016/j.suronc.2021.101561. doi: 10.1016/j.suronc.2021.101561 |
| [80] |
Rizzo G, Pafundi DP, Sionne F, D’Agostino L, Pietricola G, Gambacorta MA, et al. Preoperative chemoradiotherapy affects postoperative outcomes and functional results in patients treated with transanal endoscopic microsurgery for rectal neoplasms. Tech Coloproctol. 2021;25(3):319–31. https://doi.org/10.1007/s10151-020-02394-4. doi: 10.1007/s10151-020-02394-4 |
| [81] |
Lee W, Lee D, Choi S, Chun H. Transanal endoscopic microsurgery and radical surgery for T1 and T2 rectal cancer: retrospective study. Surg Endosc. 2003;17(8):1283–7. https://doi.org/10.1007/s00464-002-8814-x. doi: 10.1007/s00464-002-8814-x |
| [82] |
Body A, Prenen H, Lam M, Davies A, Tipping-Smith S, Lum C, et al. Neoadjuvant therapy for locally advanced rectal cancer: recent advances and ongoing challenges. Clin Colorectal Cancer. 2021;20(1):29–41. https://doi.org/10.1016/j.clcc.2020.12.005. doi: 10.1016/j.clcc.2020.12.005 |
| [83] |
Lee SH. Total neoadjuvant therapy for rectal cancer: evidence and challenge. Ann Coloproctol. 2023;39(4):301–6. https://doi.org/10.3393/ac.2023.00269.0038. doi: 10.3393/ac.2023.00269.0038 |
| [84] |
Bahadoer RR, Dijkstra EA, van Etten B, Marijnen CAM, Putter H, Kranenbarg EMK, et al. Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial. Lancet Oncol. 2021;22(1):29–42. https://doi.org/10.1016/S1470-2045(20)30555-6. doi: 10.1016/S1470-2045(20)30555-6 |
| [85] |
Conroy T, Bosset JF, Etienne PL, Rio E, François É, Mesgouez-Nebout N, et al. Neoadjuvant chemotherapy with FOLFIRINOX and preoperative chemoradiotherapy for patients with locally advanced rectal cancer (UNICANCER-PRODIGE 23): a multicentre, randomised, open-label, phase 3 trial. Lancet Oncol. 2021;22(5):702–15. https://doi.org/10.1016/S1470-2045(21)00079-6. doi: 10.1016/S1470-2045(21)00079-6 |
| [86] |
Giunta EF, Bregni G, Pretta A, Deleporte A, Liberale G, Bali AM, et al. Total neoadjuvant therapy for rectal cancer: making sense of the results from the RAPIDO and PRODIGE 23 trials. Cancer Treat Rev. 2021;96:102177. https://doi.org/10.1016/j.ctrv.2021.102177. doi: 10.1016/j.ctrv.2021.102177 |
| [87] |
Fokas E, Rödel C; German Rectal Cancer Study Group; Klautke G, Grabenbauer GG, Fietkau R. Randomized phase Ⅱ trial of chemoradiotherapy plus induction or consolidation chemotherapy as total neoadjuvant therapy for locally advanced rectal cancer: CAO/ArO/AIO-12. J Clin Oncol. 2019;37(36):3562–3. https://doi.org/10.1200/JCO.19.02179. doi: 10.1200/JCO.19.02179 |
| [88] |
Fokas E, Rödel C, Polat B, Klautke G, Grabenbauer GG, Fietkau R. Chemoradiotherapy plus induction or consolidation chemotherapy as total neoadjuvant therapy for patients with locally advanced rectal cancer: long-term results of the CAO/ARO/AIO-12 randomized clinical trial. JAMA Oncol. 2022;8(5):782–3. https://doi.org/10.1001/jamaoncol.2022.0235. doi: 10.1001/jamaoncol.2022.0235 |
| [89] |
Garcia-Aguilar J, Patil S, Gollub MJ, Kim JK, Yuval JB, Thompson HM, et al. Organ preservation in patients with rectal adenocarcinoma treated with total neoadjuvant therapy. J Clin Oncol. 2022;40(23):2546–56. https://doi.org/10.1200/JCO.22.00032. doi: 10.1200/JCO.22.00032 |
| [90] |
Benson AB, Venook AP, Al-Hawary MM, Azad N, Chen YJ, Ciombor KK, et al. Rectal cancer, version 2.2022, NCCN clinical Practice guidelines in oncology. J Natl Compr Canc Netw. 2022;20(10):1139–67. https://doi.org/10.6004/jnccn.2022.0051. doi: 10.6004/jnccn.2022.0051 |
| [91] |
Miyamoto Y, Ogawa K, Ohuchi M, Tokunaga R, Baba H. Emerging evidence of immunotherapy for colorectal cancer. Ann Gastroenterol Surg. 2023;7(2):216–24. https://doi.org/10.1002/ags3.12633. doi: 10.1002/ags3.12633 |
| [92] |
Wang Y, Shen L, Wan J, Zhang H, Wu R, Wang J, et al. Neoadjuvant chemoradiotherapy combined with immunotherapy for locally advanced rectal cancer: a new era for anal preservation. Front Immunol. 2022;13:1067036. https://doi.org/10.3389/fimmu.2022.1067036. doi: 10.3389/fimmu.2022.1067036 |
| [93] |
Le DT, Kim TW, van Cutsem E, Geva R, Jäger D, Hara H, et al. Phase Ⅱ open-label study of pembrolizumab in treatmentrefractory, microsatellite instability–high/mismatch repair–deficient metastatic colorectal cancer: KEYNOTE-164. J Clin Oncol. 2020;38(1):11–9. https://doi.org/10.1200/JCO.19.02107. doi: 10.1200/JCO.19.02107 |
| [94] |
Germani MM, Carullo M, Boccaccino A, Conca V, Masi G. The evolving landscape of immunotherapy in locally advanced rectal cancer patients. Cancers. 2022;14(18):4453. https://doi.org/10.3390/cancers14184453. doi: 10.3390/cancers14184453 |
| [95] |
Cercek A, Lumish M, Sinopoli J, Weiss J, Shia J, Lamendola-Essel M, et al. PD-1 blockade in mismatch repair-deficient, locally advanced rectal cancer. N Engl J Med. 2022;386(25):2363–76. https://doi.org/10.1056/NEJMoa2201445. doi: 10.1056/NEJMoa2201445 |
| [96] |
Trojan J, Stintzing S, Haase O, Koch C, Ziegler P, Demes M, et al. Complete pathological response after neoadjuvant shortcourse immunotherapy with ipilimumab and nivolumab in locally advanced MSI-H/dMMR rectal cancer. Oncologist. 2021;26(12):e2110–4. https://doi.org/10.1002/onco.13955. doi: 10.1002/onco.13955 |
| [97] |
Wang QX, Xiao BY, Cheng Y, Wu AW, Zhang T, Wang H, et al. Anti-PD-1-based immunotherapy as curative-intent treatment in dMMR/MSI-H rectal cancer: a multicentre cohort study. Eur J Cancer. 2022;174:176–84. https://doi.org/10.1016/j.ejca.2022.07.016. doi: 10.1016/j.ejca.2022.07.016 |
| [98] |
Sahin IH, Zhang J, Saridogan T, Gorantla V, Rhree J, Malhotra M, et al. Neoadjuvant immune checkpoint inhibitor therapy for patients with microsatellite instability-high colorectal cancer: shedding light on the future. JCO Oncol Pract. 2023;19(5):251–9. https://doi.org/10.1200/OP.22.00762. doi: 10.1200/OP.22.00762 |
| [99] |
Jones HJS, Cunningham C, Nicholson GA, Hompes R. Outcomes following completion and salvage surgery for early rectal cancer: a systematic review. Eur J Surg Oncol. 2018;44(1):15–23. https://doi.org/10.1016/j.ejso.2017.10.212. doi: 10.1016/j.ejso.2017.10.212 |
| [100] |
Junginger T, Goenner U, Hitzler M, Trinh TT, Heintz A, Wollschläger D. Local excision followed by early radical surgery in rectal cancer: long-term outcome. World J Surg Oncol. 2019;17(1):168. https://doi.org/10.1186/s12957-019-1705-6. doi: 10.1186/s12957-019-1705-6 |
| [101] |
Clermonts SHEM, Köeter T, Pottel H, Stassen LPS, Wasowicz DK, Zimmerman DDE. Outcomes of completion total mesorectal excision are not compromised by prior transanal minimally invasive surgery. Colorectal Dis. 2020;22(7):790–8. https://doi.org/10.1111/codi.14962. doi: 10.1111/codi.14962 |
| [102] |
Serra-Aracil X, Galvez Saldaña A, Mora-Lopez LL, Montes N, Pallisera-Lloveras A, Serra-Pla S, et al. Completion surgery in unfavorable rectal cancer after transanal endoscopic microsurgery: does it achieve satisfactory sphincter preservation, quality of total mesorectal excision specimen, and long-term oncological outcomes? Dis Colon Rectum. 2021;64(2):200–8. https://doi.org/10.1097/DCR.0000000000001730. doi: 10.1097/DCR.0000000000001730 |
| [103] |
Lossius WJ, Stornes T, Myklebust TA, Endreseth BH, Wibe A. Completion surgery vs. primary TME for early rectal cancer: a national study. Int J Colorectal Dis. 2022;37(2):429–35. https://doi.org/10.1007/s00384-021-04083-6. doi: 10.1007/s00384-021-04083-6 |
| [104] |
Chaouch MA, Khan J, Gill TS, Mehrabi A, Reissfelder C, Rahberi N, et al. Early salvage total mesorectal excision (sTME) after organ preservation failure in rectal cancer does not worsen postoperative outcomes compared to primary TME: systematic review and meta-analysis. Int J Colorectal Dis. 2021;36(11):2375–86. https://doi.org/10.1007/s00384-021-03989-5. doi: 10.1007/s00384-021-03989-5 |