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2011 Volume 26
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RESEARCH ARTICLE   Open Access    

A knowledge-rich distributed decision support framework: a case study for brain tumour diagnosis

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  • Corresponding authors: David Dupplaw ;  Madalina Croitoru ;  Srinandan Dasmahapatra ;  Alex Gibb ;  Horacio González-Vélez ;  Miguel Lurgi ;  Bo Hu ;  Paul Lewis ;  Andrew Peet
  • Abstract: The HealthAgents project aims to provide a decision support system for brain tumour diagnosis using a collaborative network of distributed agents. The goal is that through the aggregation of the small data sets available at individual hospitals, much better decision support classifiers can be created and made available to the hospitals taking part. In this paper, we describe the technicalities of the HealthAgents framework, in particular how the interoperability of the various agents is managed using semantic web technologies. On the broad scale the architecture is based around distributed data-mart agents that provide ontological access to hospitals’ underlying data that has been anonymized and processed from proprietary formats into a canonical format. Classifier producers have agents that gather the global data from participating hospitals such that classifiers can be created and deployed as agents. The design on a microscale has each agent built upon a generic-layered framework that provides the common agent program code, allowing rapid development of agents for the system. We believe that our framework provides a well-engineered, agent-based approach to data sharing in a medical context. It can provide a better basis on which to investigate the effectiveness of new classification techniques for brain tumour diagnosis.
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    David Dupplaw, Madalina Croitoru, Srinandan Dasmahapatra, Alex Gibb, Horacio González-Vélez, Miguel Lurgi, Bo Hu, Paul Lewis, Andrew Peet. 2011. A knowledge-rich distributed decision support framework: a case study for brain tumour diagnosis. The Knowledge Engineering Review. 26:5 doi: 10.1017/S0269888911000105
    David Dupplaw, Madalina Croitoru, Srinandan Dasmahapatra, Alex Gibb, Horacio González-Vélez, Miguel Lurgi, Bo Hu, Paul Lewis, Andrew Peet. 2011. A knowledge-rich distributed decision support framework: a case study for brain tumour diagnosis. The Knowledge Engineering Review. 26:5 doi: 10.1017/S0269888911000105

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RESEARCH ARTICLE   Open Access    

A knowledge-rich distributed decision support framework: a case study for brain tumour diagnosis

  • Corresponding authors: David Dupplaw ;  Madalina Croitoru ;  Srinandan Dasmahapatra ;  Alex Gibb ;  Horacio González-Vélez ;  Miguel Lurgi ;  Bo Hu ;  Paul Lewis ;  Andrew Peet
The Knowledge Engineering Review  26 Article number: 10.1017/S0269888911000105  (2011)  |  Cite this article

Abstract: Abstract: The HealthAgents project aims to provide a decision support system for brain tumour diagnosis using a collaborative network of distributed agents. The goal is that through the aggregation of the small data sets available at individual hospitals, much better decision support classifiers can be created and made available to the hospitals taking part. In this paper, we describe the technicalities of the HealthAgents framework, in particular how the interoperability of the various agents is managed using semantic web technologies. On the broad scale the architecture is based around distributed data-mart agents that provide ontological access to hospitals’ underlying data that has been anonymized and processed from proprietary formats into a canonical format. Classifier producers have agents that gather the global data from participating hospitals such that classifiers can be created and deployed as agents. The design on a microscale has each agent built upon a generic-layered framework that provides the common agent program code, allowing rapid development of agents for the system. We believe that our framework provides a well-engineered, agent-based approach to data sharing in a medical context. It can provide a better basis on which to investigate the effectiveness of new classification techniques for brain tumour diagnosis.

    • This research has been carried out under the HealthAgents research grant, funded by the Information Society Technologies priority of the European Union Sixth Framework Programme as a Specific Targeted Research Project with contract no.: IST-2004-27214 (2006–2008).

    • Copyright © Cambridge University Press 20112011Cambridge University Press
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    Cite this article
    David Dupplaw, Madalina Croitoru, Srinandan Dasmahapatra, Alex Gibb, Horacio González-Vélez, Miguel Lurgi, Bo Hu, Paul Lewis, Andrew Peet. 2011. A knowledge-rich distributed decision support framework: a case study for brain tumour diagnosis. The Knowledge Engineering Review. 26:5 doi: 10.1017/S0269888911000105
    David Dupplaw, Madalina Croitoru, Srinandan Dasmahapatra, Alex Gibb, Horacio González-Vélez, Miguel Lurgi, Bo Hu, Paul Lewis, Andrew Peet. 2011. A knowledge-rich distributed decision support framework: a case study for brain tumour diagnosis. The Knowledge Engineering Review. 26:5 doi: 10.1017/S0269888911000105
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