LAMIA Laboratory, French West Indies University, 97157, Pointe-à-Pitre, Guadeloupe, French West Indies; e-mails: Sebastien.Regis@univ-antilles.fr, Andrei.Doncescu@univ-antilles.fr"/> Office Surgery, 7 Rue Tah Bloudy, 97150, Marigot, Saint Martin, French West Indies; e-mail: armadadechirurgie@gmail.com"/>
Search
2023 Volume 38
Article Contents
RESEARCH ARTICLE   Open Access    

An agent-based model of COVID-19 pandemic and its variants using fuzzy subsets and real data applied in an island environment

More Information
  • Abstract: In this paper, we present a model of the spread of the COVID-19 pandemic simulated by a multi-agent system (MAS) based on demographic data and medical knowledge. Demographic data are linked to the distribution of the population according to age and to an index of socioeconomic fragility with regard to the elderly. Medical knowledge are related to two risk factors: age and obesity. The contributions of this approach are as follows. Firstly, the two aggravating risk factors are introduced into the MAS using fuzzy sets. Secondly, the worsening of disease caused by these risk factors is modeled by fuzzy aggregation operators. The appearance of virus variants is also introduced into the simulation through a simplified modeling of their contagiousness. Using real data from inhabitants of an island in the Antilles (Guadeloupe, FWI), we model the rate of the population at risk which could be critical cases, if neither social distancing nor barrier gestures are respected by the entire population. The results show that hospital capacities are exceeded. The results show that hospital capacities are exceeded. The socioeconomic fragility index is used to assess mortality and also shows that the number of deaths can be significant.
  • 加载中
  • Agence régionale de Santé de Guadeloupe (Regional Health Agency of Guadeloupe). 2020. Point de situation hebdomadaire guadeloupe (guadeloupe weekly situation update). Technical report, October 2020. https://www.guadeloupe.ars.sante.fr/coronavirus-informations-et-recommandations-0.

    Google Scholar

    Agence régionale de Santé de Guadeloupe (Regional Health Agency of Guadeloupe). 2021. Point de situation hebdomadaire guadeloupe (guadeloupe weekly situation update). Technical report, August 2021.

    Google Scholar

    Al-qaness , M. A. A., Ewees , A. A., Fan , H., Abualigah , L. & Elaziz , M. A. 2020. Marine predators algorithm for forecasting confirmed cases of Covid-19 in Italy, USA, Iran and Korea. International Journal of Environmental Research and Public Health 17 (10).

    Google Scholar

    Ali , M., Shah , S. T. H., Lmran , M. & Khan , A. 2020. The role of asymptomatic class, quarantine and isolation in the transmission of Covid-19, journal of biological dynamics. Journal of Biological Dynamics.

    Google Scholar

    Amor , M. 2020. Covid-19: a new quantified approach is a game-changer (Covid-19 : une nouvelle approche chiffrée change la donne). Frances Antilles News Papers, April 2020. https://www.guadeloupe.franceantilles.fr/actualite/sante/coronavirus/covid-19-une-nouvelle-approche-chiffree-change-la-donne-568553.php.

    Google Scholar

    Angulo , F., Finelli , L. & Swerdlow , D. L. 2021. Estimation of us sars-cov-2 infections, symptomatic infections, hospitalizations, and deaths using seroprevalence surveys. JAMA Network Open 4 (1), e2033706–e2033706.

    Google Scholar

    Badu , K., Oyebola , K., Zahouli , J. Z., Fagbamigbe , A. F., de Souza , D. K., Dukhi , N., Amankwaa , E. F., Tolba , M. F., Sylverken , A. A., Mosi , L. et al., 2021. Sars-cov-2 viral shedding and transmission dynamics: implications of who covid-19 discharge guidelines. Frontiers in Medicine, 843.

    Google Scholar

    Banerjee , A., Pasea , L., Harris , S., Gonzalez-Izquierdo , A., Torralbo , A., Shallcross , L., Noursadeghi , M., Pillay , D., Sebire , N., Holmes , C., Pagel , C., Wong , W. K., Langenberg , C., Williams , B., Denaxas , S. & Hemingway , H. 2020. Estimating excess 1-year mortality associated with the covid-19 pandemic according to underlying conditions and age: a population-based cohort study. The Lancet 395.

    Google Scholar

    Bayette , C. & Monticelli , M. 2020. Modélisation d’une épidémie, partie 1. Image des Mathématiques. https://www.washingtonpost.com/graphics/2020/world/corona-simulator/.

    Google Scholar

    Bloch , I. & Hunter , A. (eds). 2001. Fusion: general concepts and characteristics. International Journal of Intelligent Systems 16, 1107–1134.

    Google Scholar

    Bouchnita , A. & Jebrane , A. 2020. A hybrid multi-scale model of covid-19 transmission dynamics to assess the potential of non-pharmaceutical interventions. Chaos, Solitons and Fractals.

    Google Scholar

    Cai , Q., Chen , F., Wang , T., Luo , F., Liu , X., Wu , Q., He , Q., Wang , Z., Liu , Y., Liu , L., Chen , J. & Xu , L. 2020. Obesity and Covid-19 severity in a designated hospital in Shenzhen, China. Diabetes Care 43, 1392–1398.

    Google Scholar

    Carbo , J., Sanchez-Pi , N. & Molina , J. M. 2018. Agent-based simulation with netlogo to evaluate ambient intelligence scenarios. Journal of Simulation 12, 42–52.

    Google Scholar

    Carrere , P. 2010. Arterial hypertension, obesity, precariousness in guadeloupe, the CONSANT survey (HTA, obésité, précarité en Guadeloupe, l’ enquête consant). Medical thesis, http://www.hta-gwad.com/admin/publis/these_carrere_consant_ultime.pdf.

    Google Scholar

    Caussy , C., Pattou , F., Wallet , F., Simon , C., Chalopin , S., Telliam , C., Mathieu , D., Subtil , F., Frobert , E., Alligier , M., Delaunay , D., Vanhems , P., Laville , M., Jourdain , M. & Disse , E. 2020. Prevalence of obesity among adult inpatients with covid-19 in france. The Lancet Diabetes & Endocrinology 8, 562–564.

    Google Scholar

    Chimmula , V. K. R. & Zhang , L. 2020. Time series forecasting of covid-19 transmission in canada using lstm network. Chaos, Solitons and Fractals, 135.

    Google Scholar

    Chinese CDC. 2020. The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (covid-19) – China, 2020. Technical report, China CDC Weekly.

    Google Scholar

    Cuevas , E. 2020. An agent-based model to evaluate the covid-19 transmission risks in facilities. Computers in Biology and Medicine 121.

    Google Scholar

    Currie , C., Fowler , J. W., Kotiadis , K., Monks , T., Onggo , D. A. R. B. S. & Tako, A. A. 2020. How simulation modelling can help reduce the impact of covid-19. Journal of Simulation 14 (2), 83–97.

    Google Scholar

    Das , D. K., Khatua , A., Kar , T. K. & Jana , S. 2021. The effectiveness of contact tracing in mitigating covid-19 outbreak: a model-based analysis in the context of india. Applied Mathematics and Computation 404, 126207.

    Google Scholar

    Davies , N., Abbott , S., Barnard , R., Jarvis , C., Kucharski , A., Munday , J., Pearson , C., Russell , T., Tully , D., Washburne , A. et al., 2021. Estimated transmissibility and impact of sars-cov-2 lineage b. 1.1. 7 in England. Science 372 (6538).

    Google Scholar

    Dong , E., Du , H. & Gardner , L. 2020. An interactive web-based dashboard to track Covid-19 in real time. The Lancet Infectious Diseases 20 (5), 533–534.

    Google Scholar

    Dubois , D. & Prade , H. 2004. On the use of aggregation operations in information fusion process. Fuzzy Sets and Systems 142, 143–161.

    Google Scholar

    Duong , D. 2021. Alpha, beta, delta, gamma: what’s important to know about sars-cov-2 variants of concern? CMAJ 193 (27). doi: 10.1503/cmaj.1095949.

    CrossRef   Google Scholar

    Escabí , M. 2012. Biosignal Processing. In Introduction to Biomedical Engineering, 3rd edition, Biomedical Engineering 11.

    Google Scholar

    Flaxman , S., Mishra , S., Gandy , A., Unwin , H., Coupland , H., Mellan , T., Zhu , H., Berah , T., Eaton , J., Guzman , P. P., Schmit , N., Cilloni , L., Ainslie , K., Baguelin , M., Blake , I., Boonyasiri , A., Boyd , O., Cattarino , L., Ciavarella , C., Cooper , L., Perez , Z. C., Cuomo-Dannenburg , G., Dighe , A., Djaafara , A., Dorigatti , I., Elsland , S. V., Fitzjohn , R. R., Fu , H., Gaythorpe , K., Geidelberg , L., Grassly , N., Green , W., Hallett , T., Hamlet , A., Hinsley , W., Jeffrey , B., Jorgensen , D., Knock , E., Laydon , D., Gilani , G. N., Nouvellet , P., Parag , K., Siveroni , I., Thompson , H., Verity , R., Volz , E., Walters , C., Wang , H., Wang , Y., Watson , O., Winskill , P., Xi , X., Whittaker , C., Walker , P., Ghani , A., Donnelly , C., Riley , S., Okell , L., Vollmer , M., Ferguson , N. & Bhatt , S. 2020. Estimating the Number of Infections and the Impact of Non-Pharmaceutical Interventions on Covid-19 in 11 European Countries. Technical report, Imperial College London. https://doi.org/10.25561/77731.

    Google Scholar

    Fong , S. J., Li , G., Crespo , N. D. R. & Herrera-Viedma , E. 2020. Composite Monte Carlo decision making under high uncertainty of novel coronavirus epidemic using hybridized deep learning and fuzzy rule induction. Applied Soft Computing Journal 93.

    Google Scholar

    Food and Agriculture Organization of the United Nations Regional Office for Latin America and the Caribbean. 2019. United Nations Calls for Urgent Action to Curb the Rise in Hunger and Obesity in Latin America and the Caribbean. Technical report, UN. http://www.fao.org/americas/noticias/ver/en/c/1250656/.

    Google Scholar

    Gao , F., Zheng , K., Wang , X., Sun , Q.-F., Pan , K.-H., Wang , T.-Y., Chen , Y.-P., Targher , G., Byrne , C. D., George , J. & Zheng , M.-H. 2020. Obesity is a risk factor for greater Covid-19 severity. Diabetes Care.

    Google Scholar

    Giordano , G., Blanchini , F., Bruno , R., Colaneri , P., Filippo , A. D., Matteo , A. D. & Colaneri , M. 2020. Modelling the Covid-19 epidemic and implementation of population-wide interventions in italy. Nature Medicine 26, 855–860.

    Google Scholar

    Haut Conseil de la santé publique (France). 2020. Opinion on the prevention and management of patients at risk for serious forms of Covid-19 as well as the prioritization of diagnostic tests (avis relatif à la prévention et à la prise en charge des patients à risque de formes graves de Covid-19 ainsi qu’à la priorisation des tests diagnostiques). Technical report.

    Google Scholar

    I. N. S. E. E. National Institute of Statistics & Economic Studies of France. 2015. Complete File of the Department of Guadeloupe (dossier complet du département de la guadeloupe). Technical report, INSEE. https://www.insee.fr/fr/statistiques/2011101?geo=DEP-971.

    Google Scholar

    Ivorra , B., Ferrández , M., Vela-Pérez , M. & Ramos , A. 2020. Mathematical modeling of the spread of the coronavirus disease 2019 (COVID-19) taking into account the undetected infections. The case of China. Communications in Nonlinear Science and Numerical Simulation, 88.

    Google Scholar

    Jagodnik , K. M., Ray , F., Giorgi , F. M. & Lachmann , A. 2020. Correcting under-reported covid-19 case numbers: estimating the true scale of the pandemic. medRxiv preprint.

    Google Scholar

    Jensen , N., Kelly , A. & Avendano , M. 2021. The Covid-19 pandemic underscores the need for an equity-focused global health agenda. Humanities and Social Sciences Communications 8 (1), 1–6.

    Google Scholar

    Kass , D. A., Duggal , P. & Cingolani , O. 2020. Obesity could shift severe Covid-19 disease to younger ages. The Lancet 395, 1544.

    Google Scholar

    Korber , B., Fischer , W., Gnanakaran , S., Yoon , H., Theiler , J., Abfalterer , W., Hengartner , N., Giorgi , E., Bhattacharya , T., Foley , B., et al., 2020. Tracking changes in sars-cov-2 spike: evidence that d614g increases infectivity of the Covid-19 virus. Cell 182 (4), 812–827.

    Google Scholar

    Lighter , J., Phillips , M., Hochman , S., Sterling , S., Johnson , D., Francois , F. & Stachel , A. 2020. Obesity in patients younger than 60 years is a risk factor for Covid-19 hospital admission. Oxford University Press PHEC.

    Google Scholar

    Ma , X. & Vervoort , D. 2020. Critical care capacity during the covid-19 pandemic: global availability of intensive care beds. Journal of Critical Care 58, 96–97.

    Google Scholar

    Mahase , E. 2020. Covid-19: why are age and obesity risk factors for serious disease? BMJ 371. https://www.bmj.com/content/371/bmj.m4130.

    Google Scholar

    Mahmood , I., Arabnejad , H., Suleimenova , D., Sassoon , I., Marshan , A., Serrano-Rico , A., Louvieris , P., Anagnostou , A., Taylor , S., Bell , D. & Groen , D. 2020. Facs: a geospatial agent-based simulator for analysing Covid-19 spread and public health measures on local regions. Journal of Simulation.

    Google Scholar

    Matsumoto , M. & Nishimura , T. 1998. Mersenne twister: a 623-dimensionally equidistributed uniform pseudo-random number generator. ACM Transactions on Modeling and Computer Simulation.

    Google Scholar

    McLennan , A. K. & Ulijaszek , S. J. 2015. Obesity emergence in the Pacific islands: why understanding colonial history and social change is important. Public Health Nutrition.

    Google Scholar

    Miyahira , S. A. & Araujo , E. 2008. Fuzzy obesity index for obesity treatment and surgical indication. In 2008 IEEE International Conference on Fuzzy Systems.

    Google Scholar

    Miyahira , S. A., de Azevedo , J. L. M. C. & Araujo , E. 2011. Fuzzy obesity index (MAFOI) for obesity evaluation and bariatric surgery indication. Journal of Translational Medicine, 9.

    Google Scholar

    Muscogiuri , G., Pugliese , G., Barrea , L., Savastano , S. & Colao , A. 2020. Obesity: the “achilles heel” for covid-19? Metabolism Clinical and Experimental 108.

    Google Scholar

    Noll , N. B., Aksamentov , I., Druelle , V., Badenhorst , A., Ronzani , B., Jefferies , G., Albert , J. & Neher , R. A. 2020a. Covid-19 scenarios: an interactive tool to explore the spread and associated morbidity and mortality of sars-cov-2. medRxiv.

    Google Scholar

    Noll , N. B., Aksamentov , I., Druelle , V., Badenhorst , A., Ronzani , B., Jefferies , G., Albert , J. & Neher , R. A. 2020b. Covid-19 Scenarios. Technical report. https://covid19-scenarios.org/.

    Google Scholar

    Nouvellet , P., Bhatia , S., Cori , A., Ainslie , K. E. C., Baguelin , M., Bhatt , S., Boonyasiri , A., Brazeau , N. F., Cattarino , L., Cooper , L. V., Coupland , H., Cucunuba , Z. M., Cuomo-Dannenburg , G., Dighe , A., Djaafara , B. A., Dorigatti , I., Eales , O. D., van Elsland , S. L., Nascimento , F. F., FitzJohn , R. G., Gaythorpe , K. A. M., Geidelberg , L., Green , W. D., Hamlet , A., Hauck , K., Hinsley , W., Imai , N., Jeffrey , B., Knock , E., Laydon , D. J., Lees , J. A., Mangal , T., Mellan , T. A., Nedjati-Gilani , G., Parag , K. V., Pons-Salort , M., Ragonnet-Cronin , M., Riley , S., Unwin , H. J. T., Verity , R., Vollmer , M. A. C., Volz , E., Walker , P. G. T., Walters , C. E., Wang , H., Watson , O. J., Whittaker , C., Whittles , L. K., Xi , X., Ferguson , N. M. & Donnelly , C. A. 2020. Reduction in Mobility and Covid-19 Transmission. Technical report, Imperial College London. https://doi.org/10.25561/79643.

    Google Scholar

    Observatoire des fragilités (Fragility Observatory). 2020. Carte des fragilités (fragility map). http://www.observatoiredesfragilites.fr/.

    Google Scholar

    Observatoire National des fragilités (France) National Observatory of Fragility of France. 2020. Guadeloupe regional fragility observatory (observatoire régional des fragilités de guadeloupe). Technical report, INSEE. https://www.observatoires-fragilites-grand-sud.fr.

    Google Scholar

    O’Driscoll , M., Santos , G. R. D., Wang , L., Cummings , D. A., Azman , A. S., Paireau , J., Fontanet , A., Cauchemez , S. & Salje , H. 2021. Age-specific mortality and immunity patterns of sars-cov-2. Nature 590 (7844), 140–145.

    Google Scholar

    Pearson , C., Russell , T., Davies , N., Kucharski , A., C. C.-. Working Group, Edmunds, W., Eggo , R., et al., 2021. Estimates of severity and transmissibility of novel south africa sars-cov-2 variant 501y. V2. Retrieved from: pdf (cmmid. github. io).

    Google Scholar

    Petrilli , C., Jones , S., Yang , J., Rajagopalan , H., O’Donnell , L., Chernyak , Y., Tobin , K., Cerfolio , R. J., Francois , F. & Horwitz , L. I. 2020. Factors associated with hospitalisation and critical illness among 5279 patients with coronavirus disease 2019 in new york city prospective cohort study. BMJ 369.

    Google Scholar

    Pettit , N. N., MacKenzie , E. L., Ridgway , J. P., Pursell , K., Ash , D., Patel , B. & Pho , M. T. 2020. Obesity is associated with increased risk for mortality among hospitalized patients with Covid-19. Obesity 28, 1806–1810.

    Google Scholar

    Radio Caraïbes Internationale. 2021. Les gestes barrières ont permis d’éviter une catastrophe sanitaire selon une étude (barrier gestures helped prevent a health disaster according to a study). https://www.rci.fm/guadeloupe/infos/Sante/Les-gestes-barrieres-ont-permis-deviter-une-catastrophe-sanitaire-selon-une-etude.

    Google Scholar

    Rahmandad , H., Lim , T. & Sterman , J. 2021. Behavioral dynamics of covid-19: estimating underreporting, multiple waves, and adherence fatigue across 92 nations. System Dynamics Review 37 (1), 5–31.

    Google Scholar

    Rao , S. & Singh , M. 2021. The newly detected b. 1.1. 529 (omicron) variant of sars-cov-2 with multiple mutations: implications for transmission, diagnostics, therapeutics, and immune evasion. DHR Proceedings 1 (S5), 7–10.

    Google Scholar

    Régis , S., Manicom , O. & Doncescu , A. (2020a). Use of fuzzy sets, aggregation operators and multi agent systems to simulate COVID-19 transmission in a context of absence of barrier gestures and social distancing: application to an island region. In IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2020, Virtual Event, South Korea, December 16–19, 2020, Park , T., Cho , Y., Hu , X., Yoo , I., Woo , H. G., Wang , J., Facelli , J. C., Nam , S. & Kang , M. (eds), 2298–2305. IEEE.

    Google Scholar

    Régis , S., Manicom , O. & Doncescu , A. (2020b). Softcomputing tools for simulating Covid-19 transmission without barrier gestures. The case of guadeloupe. In IEEE/IIAI International Congress on Applied Information Technology, AIT 2020, Virtual Event, December 10–20, 2020.

    Google Scholar

    Roda , W. C., Varughese , M. B., Han , D. & Li , M. Y. 2020. Why is it difficult to accurately predict the Covid-19 epidemic? Infectious Disease Modelling 5, 271–281.

    Google Scholar

    Roques , L., Klein , E. K., Papax , J., Sara , A. & Soubeyrand , S. 2020. Using early data to estimate the actual infection fatality ratio from Covid-19 in France. Biology, 9.

    Google Scholar

    Roussel , I. 2021. Covid-19 in France: the revenge of the countryside. In Coronavirus (COVID-19) Outbreaks, Environment and Human Behaviour, 195–219.

    Google Scholar

    Roux , J., Massonnaud , C. & Crépey , P. 2020. Covid-19: one-month impact of the French lockdown on the epidemic burden. medRxiv, preprint. https://doi.org/10.1101/2020.04.22.20075705.

    Google Scholar

    Rustam , F., Reshi , A. A., Mehmood , A., Ullah , S., On , B., Aslam , W. & Choi , G. S. 2020. Covid-19 future forecasting using supervised machine learning models. IEEE Access 8, 101489–101499.

    Google Scholar

    Salje , H., Kiem , C. T., Lefrancq , C., Courtejoie , N., Bosetti , P., Paireau , J., Andronico , A., Hozé , N., Richet , J., Dubost , C.-L., Strat , Y. L., Lessler , J., Levy-Bruhl , D., Fontanet , A., Opatowski , L., Boelle , P.-Y. & Cauchemez , S. 2020. Estimating the burden of sars-cov-2 in France. Science.

    Google Scholar

    Séné , L. & Pétrine , P. 2020. Coronavirus: much larger real numbers here (coronavirus: Des chiffres réels beaucoup plus importants chez nous). Guadeloupe 1ière TV. https://la1ere.francetvinfo.fr/guadeloupe/coronavirus-des-chiffres-reels-beaucoup-plus-importants-chez-nous-821842.html.

    Google Scholar

    Shamasunder , S., Holmes , S. M., Goronga , T., Carrasco , H., Katz , E., Frankfurter , R. & Keshavjee , S. 2020. Covid-19 reveals weak health systems by design: why we must re-make global health in this historic moment. Global Public Health 15 (7), 1083–1089.

    Google Scholar

    Shen , K., Loomer , L., Abrams , H., Grabowski , D. C. & Gandhi , A. 2021. Estimates of COVID-19 cases and deaths among nursing home residents not reported in federal data. JAMA Network Open 4 (9).

    Google Scholar

    Shuja , J., Alanazi , E., Alasmary , W. & Alashaikh , A. 2020. Covid-19 open source data sets: a comprehensive survey. Applied Intelligence.

    Google Scholar

    Silva , P., Batista , P., Lima , H., Alves , M., Guimaraes , F. & Silva , R. 2020. Covid-abs: an agent-based model of covid-19 epidemic to simulate health and economic effects of social distancing interventions. Chaos, Solitons and Fractals, 139.

    Google Scholar

    Smith , M. & Broniatowski , D. 2016. Modeling influenza by modulating flu awareness. In Social, Cultural, and Behavioral Modeling. SBP-BRiMS, Xu , K., Reitter , D., Lee , D. & Osgood , N. (eds), Lecture Notes in Computer Science 9708.

    Google Scholar

    Steven , H. 2020. Why outbreaks like coronavirus spread exponentially, and how to “flatten the curve”. The Washinton Post. https://www.washingtonpost.com/graphics/2020/world/corona-simulator/.

    Google Scholar

    Tatapudi , H., Das , R. & Das , T. 2020. Impact assessment of full and partial stay-at-home orders, face mask usage, and contact tracing: an agent-based simulation study of Covid-19 for an urban region. Global Epidemiology, 2.

    Google Scholar

    Verity , R., Okell , L. C., Dorigatti , I., Winskill , P., Whittaker , C., Imai , N., Cuomo-Dannenburg , G., Thompson , H., Walker , P. G. T., Fu , H., Dighe , A., Griffin , J. T., Baguelin , M., Bhatia , S., Boonyasiri , A., Cori , A., Cucunubá , Z., FitzJohn , R., Gaythorpe , K., Green , W., Hamlet , A., Hinsley , W., Laydon , D., Nedjati-Gilani , G., Riley , S., van Elsland , S., Volz , E., Wang , H., Wang , Y., Xi , X., Donnelly , C. A., Ghani , A. C. & Ferguson , N. M. 2020. Estimates of the severity of coronavirus disease 2019: a model-based analysis. The Lancet Infectious Diseases 20.

    Google Scholar

    Volz , E., Mishra , S., Chand , M., Barrett , J., Johnson , R., Geidelberg , L., Hinsley , W., Laydon , D., Dabrera , G., O’Toole , Á., et al., 2021. Assessing transmissibility of sars-cov-2 lineage b. 1.1. 7 in england. Nature, 1–17.

    Google Scholar

    Vyklyuk , Y., Manylich , M., Skoda , M., Radovanovic , M. M. & Petrovic , M. D. 2021. Modeling and analysis of different scenarios for the spread of Covid-19 by using the modified multi-agent systems - evidence from the selected countries. Results in Physics, 20.

    Google Scholar

    Wang , Z., Zhao , H., Lai , Z. & Qin , X. 2016. Improved sir epidem model of social network marketing effectiveness and experimental simulation. Xitong Gongcheng Lilun yu Shijian/System Engineering Theory and Practice 36, 2024–2034.

    Google Scholar

    Wilensky , U. 1999. Netlogo. Technical report, Center for Connected Learning and Computer-Based Modeling, Northwestern University, Evanston, IL. http://ccl.northwestern.edu/netlogo/.

    Google Scholar

    Williamson , E., Walker , A. J., Bhaskaran , K., Bacon , S., Bates , C., Morton , C. E., Curtis , H. J., Mehrkar , A., Evans , D., Inglesby , P., Cockburn , J., McDonald , H. I., MacKenna , B., Tomlinson , L., Douglas , I. J., Rentsch , C. T., Mathur , R., Wong , A., Grieve , R., Harrison , D., Forbes , H., Schultze , A., Croker , R., Parry , J., Hester , F., Harper , S., Perera , R., Evans , S., Smeeth , L. & Goldacre , B. 2020. Opensafely: factors associated with covid-19-related hospital death in the linked electronic health records of 17 million adult nhs patients. medRxiv preprint. https://doi.org/10.1101/2020.05.06.20092999.

    Google Scholar

    Wu , J., Leung , K., Bushman , M., Kishore , N., Niehus , R., de Salazar , P. M., Cowling , B. J., Lipsitch , M. & Leung , G. M. 2020. Estimating clinical severity of covid-19 from the transmission dynamics in Wuhan, China. Nature Medicine 26, 506–510.

    Google Scholar

    Wu , Z. & McGoogan , J. M. 2020. Characteristics of and important lessons from the coronavirus disease 2019 (Covid-19) outbreak in China. JAMA.

    Google Scholar

    Yager , R. 1988. On ordered weighted averaging operators in multi-criteria decision making. IEEE Trans. Systems, Man, and Cybernetics 28, 183–190.

    Google Scholar

    Yager , R. & Rybalov , A. 1998. Full reinforcement operators in aggregation techniques. IEEE Transactions on Systems, Man, Cybernetics-Part B : Cybernetics.

    Google Scholar

    Yang , C. & Wilensky , U. 2011a. Netlogo Epidem Travel and Control Model. Technical report, Center for Connected Learning and Computer-Based Modeling, Northwestern University, Evanston, IL. http://ccl.northwestern.edu/netlogo/models/epiDEMTravelandControl.

    Google Scholar

    Yang , C. & Wilensky , U. 2011b. Netlogo Epidem Basic. Technical report, Center for Connected Learning and Computer-Based Modeling, Northwestern University, Evanston, IL. https://ccl.northwestern.edu/netlogo/models/epiDEMBasic.

    Google Scholar

    Zadeh , L. 2011. Fuzzy Set Theory and Probability Theory: What is the Relationship?. Springer Berlin Heidelberg, 563–566. ISBN 978-3-642-04898-2. doi: https://doi.org/10.1007/978-3-642-04898-2_614.

    Google Scholar

    Zhou , F., Yu , T., Du , R., Fan , G., Liu , Y., Liu , Z., Xiang , J., Wang , Y., Song , B., Gu , X., Guan , L., Wei , Y., Li , H., Wu , X., Xu , J., Tu , S., Zhang , Y., Chen , H. & Cao , B. 2020. Clinical course and risk factors for mortality of adult inpatients with Covid-19 in Wuhan, China: a retrospective cohort study. The Lancet 395, 1054–1062.

    Google Scholar

  • Cite this article

    Sébastien Regis, Olivier Manicom, Andrei Doncescu. 2023. An agent-based model of COVID-19 pandemic and its variants using fuzzy subsets and real data applied in an island environment. The Knowledge Engineering Review 38(1), doi: 10.1017/S0269888923000036
    Sébastien Regis, Olivier Manicom, Andrei Doncescu. 2023. An agent-based model of COVID-19 pandemic and its variants using fuzzy subsets and real data applied in an island environment. The Knowledge Engineering Review 38(1), doi: 10.1017/S0269888923000036

Article Metrics

Article views(80) PDF downloads(31)

Other Articles By Authors

RESEARCH ARTICLE   Open Access    

An agent-based model of COVID-19 pandemic and its variants using fuzzy subsets and real data applied in an island environment

Abstract: Abstract: In this paper, we present a model of the spread of the COVID-19 pandemic simulated by a multi-agent system (MAS) based on demographic data and medical knowledge. Demographic data are linked to the distribution of the population according to age and to an index of socioeconomic fragility with regard to the elderly. Medical knowledge are related to two risk factors: age and obesity. The contributions of this approach are as follows. Firstly, the two aggravating risk factors are introduced into the MAS using fuzzy sets. Secondly, the worsening of disease caused by these risk factors is modeled by fuzzy aggregation operators. The appearance of virus variants is also introduced into the simulation through a simplified modeling of their contagiousness. Using real data from inhabitants of an island in the Antilles (Guadeloupe, FWI), we model the rate of the population at risk which could be critical cases, if neither social distancing nor barrier gestures are respected by the entire population. The results show that hospital capacities are exceeded. The results show that hospital capacities are exceeded. The socioeconomic fragility index is used to assess mortality and also shows that the number of deaths can be significant.

    • This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
References (88)
  • About this article
    Cite this article
    Sébastien Regis, Olivier Manicom, Andrei Doncescu. 2023. An agent-based model of COVID-19 pandemic and its variants using fuzzy subsets and real data applied in an island environment. The Knowledge Engineering Review 38(1), doi: 10.1017/S0269888923000036
    Sébastien Regis, Olivier Manicom, Andrei Doncescu. 2023. An agent-based model of COVID-19 pandemic and its variants using fuzzy subsets and real data applied in an island environment. The Knowledge Engineering Review 38(1), doi: 10.1017/S0269888923000036
  • Catalog

      /

      DownLoad:  Full-Size Img  PowerPoint
      Return
      Return